Osteogenesis Imperfecta (OI)

Osteogenesis Imperfecta (OI)

Osteogenesis Imperfecta (OI), commonly known as “brittle bone” disorder is a genetic disorder characterized by bones that break easily, often with little cause. People with OI may also have teeth problems (dentinogenesis imperfecta), and hearing loss when they are adults. People who have OI may also have muscle weakness, loose joints (joint laxity) and skeletal malformations.


Osteogenesis Imperfecta Foundation 

An organization founded and managed by people with osteogenesis impertfecta and parents of people with OI. The Foundation publishes “Breakthrough” (a quarterly newsletter); provides literature and videos upon request; holds national conferences, local and regional meetings; has a peer contact network; and accepts contributions to support education, awareness, and research.
804 West Diamond Avenue, Suite 210
Gaithersburg, MD 20878
Phone: 301-947-0083 or (844) 889-7579
Massachusetts support: 508-292-0562 (South Shore Group)
Email: bonelink@oif.org

Other Information:

Osteogenesis ImperfectaGenetics Home Reference 

Osteogenesis Imperfecta in ChildrenBoston Children’s Hospital

Learning About Osteogenesis ImperfectaNational Human Genome Research Institute

Osteogenesis ImperfectaAmerican Academy of Orthopedic Surgeons

Osteogenesis Imperfecta (Brittle Bone Disease)Nemours KidsHealth

Fact Sheet last updated on: 3/21/2023


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